Impurities Baccatin, Analytical Standards of Baccatin, Cas # 32981-86-5| Drug Impurities

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10-Deacetylbaccatin III

10-Deacetylbaccatin III

Product Details of '10-Deacetylbaccatin III'

Catalog Number DI-O-31076

Category Impurities

CAS Number 32981-86-5

Molecular Weight 544.59

Molecular Formula C29H36O10

Application Notes "Impurity in commerial preparation of Baccatin.;Impurity in commercial preparations of Baccatin. Cabazitaxel intermediate. 10-Deacetylbaccatin III is an inhibitor of microtubule assembly (IC50s = 23 and 0.9 ?M for porcine brain and Physaram microtubules, respectively) found in T. baccata extracts.1 It is a precursor in the semisynthetic synthesis of paclitaxel (Item No. 10461) and other semisynthetic toxoids.2 10-Deacetylbaccatin III also selectively inhibits growth of L. donovani intracellular amastigotes within J774 murine macrophages (IC50 = 70 nM), while having no effect on macrophage morphology.3"

References "Lataste, H,,Senilh, V,,Wright, M,, et al; Proc, Natl, Acad, Sci, USA 81(13), 4090-4094 (1984),"

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10-Deacetylbaccatin III
Chemical Compounds

Impurities

10-Deacetylbaccatin III

Keywords:Impurities of Baccatin,Impurity of Baccatin,Baccatin impurities, Cas no 32981-86-5,Analytical Standards of Baccatin,Baccatin EP Impurities,
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