Home > Sofosbuvir 3�,5�-Bis-(S)-phosphate
Sofosbuvir 3’,5’-Bis-(S)-phosphate

Sofosbuvir 3�,5�-Bis-(S)-phosphate

Cat. No. DIT-84999
CAS. No. 1337482-17-3
Category Impurities
Stock Status IN-Stock
Molecular Formula C34H45FN4O13P2
Molecular Weight 798.69 mol/g
Application Sofosbuvir 3',5'-Bis-(S)-phosphate is an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-�-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.