Cat. No. | DIT-84999 |
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CAS. No. | 1337482-17-3 |
Category | Impurities |
Stock Status | IN-Stock |
Molecular Formula | C34H45FN4O13P2 |
Molecular Weight | 798.69 mol/g |
Application | Sofosbuvir 3',5'-Bis-(S)-phosphate is an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-�-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. |